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Traditional Chinese Medicine (TCM) involves the use of Chinese herbal medicine, Acupuncture, Moxibustion, Qi gong, Tuina (Chinese massage), and a medicated diet, and is one of the world's most ancient medical systems, with its own principles, diagnostic methods and

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

therapies. It has become very popular in the west.

Meridians and Collaterals

TCM views the meridians and collaterals networks using Zang-Fu, which categorises tissues and organs in an organic whole. Each Zang and Fu organ transports Qi and blood, and regulates Y

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

in and Yang, maintaining the functions and activities of all parts of the body. This system guides the diagnosis, treatment and application of all the branch subjects of TCM.

Yin and Yang

TCM also holds as its central belief that health in all parts of body is du

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e to the relationship between Yin and Yang. Yin and Yang theory is the general principle used to classify in TCM's holistic approach to health and disease, and also offers a clinical guide to preventing and curing disease.

Diagnosis

TCM's diagnosis depends merely

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

on the doctor's sense organs to acquire clinical data. It mainly consists of the four techniques of diagnosis, namely: interrogation, inspection, auscultation (listening) and olfaction (smelling), pulse feeling and palpation.

Treatment

TCM has three basic compon

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nts: Chinese herbal therapy, Acupuncture and Tuina (Chinese massage) therapy, and Diet therapy.

Chinese herbal therapy

This is based on the principle that good health depends on achieving optimum vitality and balance – a balance described in terms of the polarity

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

of Yin and Yang.

Chinese herbs come from nature, and include flowers, stems, leaves, roots and barks. Each herb has its own specific characteristics. Their different characteristics are employed to treat disease, rectify the hyperactivity or hypoactivity of Yin o

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r Yang, and help the body restore its normal physiological functions - consequently, curing the disease and restoring health.

Chinese herbal administration (herbal dosages and powder forms) usually depends on your condition, your constitution and age. It should be

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

larger for serious emergencies and stubborn problems with a young and strong patient, smaller for mild problems, and with the aged, the frail, and with children and pregnant women.

The doctor will carefully select different herbal dosages or powder forms to treat

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

you as your treatment starts, and closely monitor your progress through regular consultations. As your condition change, the treatment will be altered accordingly.

Acupuncture and Tuina therapy

These are two practical therapies in TCM. They are to regulate the m

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ridians or channels of the body, to unblock the stagnation of Qi and blood, and balance Yin and Yang, maintaining their function, via the extraordinary points, scalp points, auricular points, and other special points by needle (in the case of Acupuncture) or by the

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

fingers, hands and limbs of the Tuina therapist.

When using Tuina for infant and prenatal care, some special points exist besides the acupoints on the 14 meridians and extra-points. Manipulation using pushing, kneading, rubbing is mostly used. measuring the wais

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

tline

Diet Therapy

Each food (vegetable, fruit, meal, nut, etc.) has its own specific characteristics. We can guide you to the best foods to treat your condition, in accordance with the actual condition of disease, the characters and functions of the foods, and t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

herapeutic requirements found through the doctor's consultation.

Other treatments

Moxibustion, Cupping therapy, Ear authority, Electrolysis, Electrotherapy (without needle) are often used. All of them work by same principles of acupuncture therapy.

What does Chi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

nese Medicine treat?

TCM treats your mind and body as a whole, not just the condition. Using the principles of TCM, a very wide variety of conditions, and any age can be helped, including:

1.Common Internal Diseases

Anaemia, Asthma, Arthritis, Cerebral Thrombosi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

, Cold, Colitis, Constipation, Constipation, Cholecystitis, Coronary Heart Disease, Digestive Ulcers, Diabetes, Diarrhoea, Oedema, Flu, Gout, Headaches, Hypertension, Hyperlipoproteinemia, Hay fever, Irritable bowel syndrome, Malabsorption, Nephritis, Neurosis, Neu

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rasthenia, Thyroid, Pneumonia, Pancreatitis, etc.

2.Women's problems

Pre-menstrual syndrome, Painful periods, Menopausal syndromes, endometriosis, Sterility, Morning sick, Pelvic Inflammation, etc.

3.Men's problems

Ejaculation Praecox, Hypertrophy, Low Steam Co

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

urt, Impotence, Prostitutes, Sex Drive Problems.

4.Skin problems

Herpes Zoster, Contact Dermatitis, Eczema, Urticaria, Neurodermatitis, Psoriasis, Acne Vulgaris, Alopecia Areata, Resaca, etc.

5.Muscular, neurological, skeletal and vascular problems

Arthritis, B

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ack Pain, Frozen Shoulder, Gonitis, Hemiplegia, Lumbago (lower back pain), Neuralgia, Omalgia, Sciatica, Stiff Neck Stroke, Sprain, Sports Injury, Tennis Elbow, Trigeminal, Tendon Injury, etc.

6.Mental and Emotional Problems

Anxiety, Depression, Stress, Panic Att

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ack, Insomnia, Palpitation, etc.

7.Ear, Nose, Throat and Ophthalmic Problems

Conjunctivitis, Optic Neuritis, Myopia, Obits Media, Sore Throat, Hay Fever, Halitosis, Pharyngitis, Rhinitis, Sinusitis, etc.

8.Oncology

Liver Cancer, Lung Cancer, Gastric Cancer, etc

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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