Advice Pool - Health and Fitness

If you are vexed by the issue of whether to circumcise or not, you are not alone. Randomly approach two women from a crowded street and as them

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

if they prefer a circumcised man or an uncircumcised man, you will know what I mean. Ok, you may get slapped for that but assume that you are no

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

, you will find that the vote is equally split.

If that's the case, why do some men prefer to take away the foreskin of the penis? Or why do so

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e women prefer their men be natural with the foreskin firmly intact?

Here are the pros and cons of having a circumcised penis:

Pros :-

1) A c

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rcumcized penis is cleaner as the troublesome foreskin is not there to trap dirt, urine, semen, whatever. Some women prefer a clean-cut penis h

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ad for hygienic reasons. One woman says : "Based on my previous encounters, cleanliness is important because the penis tastes, smells, and looks

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

more appealing. Plus, spur-of-the-moment sexual activity is more enjoyable with a man who is circumcised, because bathing efforts last for longe

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

periods of time."

2) A circumcized penis is more sexy looking? This is actually a subjective take. Some girls prefer bald men, right?

3) A c

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rcumcised penis is more sensitive to the touch, so it is more pleasurable for both parties involved. The penis head contains lots of nerve cell

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

that are sensitive and without the foreskin, things can get really "sex-citing"

4) A circumcised penis sits neatly in a condom. It does not ge

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

in the way during thrusting and holds on to the condom more tightly. Thus it is safer for you and your partner too.

Cons:-

1) A circumcised

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

penis is not natural, its not meant to be that way.

2) Some women prefer the feel of the extra skin, especially during foreplay. One woman sur

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eyed says: "Although I do base my opinion of a man on his big head, not his little one, I have to say that uncircumcised is better because there

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

is more variation. Playing with the skin is like an added benefit, it feels comfortable while he is thrusting also. From my experience, cut peni

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

es tends to rub too hard and too much. A little friction is good, but too much can be quite painful. Uncut guys give just the right amount of fr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ction and I like the way the skin moves back and forth in my mouth."

3) A circumcised penis may hurt during lovemaking as it is not protected

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

by the foreskin

As you can see, this is really a personal choice. There are advantages and disadvantages associated with having a circumcised p

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nis but in the end, it is up to you (and your partner) to decide which way to go.

Religious reasons aside, a circumcised penis is more hygienic

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

and easier to maintain, so to speak. On the flip side, the penis may become too sensitive without the foreskin and can hurt. So unless you are a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

masochist (or your partner is a sadist?), you may want think carefully.

Me? I'm scared of pain and prefer the "organic way". But that's just me

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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