Advice Pool - Health and Fitness

Neurobics is a term invented by Lawrence Katz and Manning Rubin to describe exercises that help the brain stay fit.

Specific types of sensory stimuli

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

and activities, especially those that involve non-routine actions and thoughts, produce more of the chemicals that encourage growth of new dendrites

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and neurons in the brain. Routine activities become so automatic that they are done largely unconsciously (ever get up in the morning and walk to the

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

kitchen before you are really conscious?). This means they require less activity in the brain, and exercise it less.

Therefore, a neurobic activity s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hould do one or more of the following:

1. Involve one or more senses in a new context.

2. Involve your full attention.

3. Break your routine in a s

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ignificant way.

Neurobics do not have to be complicated. They also don't require that you set aside special times for them. As long as they follow th

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e guidelines above, many simple activities make for good brain exercises, and can be worked into your normal day.

Some Brain Exercises or Neurobic

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Learn braille. This is a tough one, but learning to read with your fingers definitely involves one of your senses in a new context.

Do somethin

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

g in a new environment. Go to a new park, or a new store. Travel, by the way, seems to slow age-related mental decline.

Leave the lights off. Get aro

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

und your home by memory and feel. This certainly fully engages your attention, but be careful of course.

New odors in the morning. Have new odors, li

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ke a bottle of mint extract ready to smell first thing in the morning, to "wake up" your brain.

Shower with your eyes closed. Your other senses becom

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e more active when you cannot see, and a shower engages several senses.

Brush your teeth with your non-dominant hand. This is difficult for some of u

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s, and requires full attention the first time you try it.

Wear different clothes. Ever notice how you feel differently when you wear different clothe

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s. You may think differently as well. Give it a try.

Choose to respond differently. Catch yourself in a normal and mostly unconscious response to a s

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tuation, and choose to respond in a different (preferably better) way.

Take a new route to work. It doesn't have to be a longer route - just differen

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t. You may even find a faster way to work once you break your routine.

Act confident. In a situation you are unsure about, choose to act confidently.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

You'll notice that your mind gets very active once you adopt the assumption that you will know what to do.

Learn to distinguish coins using only you

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r sense of touch. This brain exercise can be a way to kill time when waiting for an appointment. If you really want a challenge, see if you can distin

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

guish paper currency denominations by touch.

Of course following the simple guidelines above (involve your full attention, use one or more of your se

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nses in a new context, or break your routine in a significant way) you can invent your own neurobics routine. Have some fun with these brain exercises

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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