Advice Pool - Health and Fitness

Laser hair removal therapy is the most permanent hair removal therapy or technique to get rid of unwanted body hair. This is a ver

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

y lengthy method and requires the candidate to have many sessions of the treatment before adequate results are attained. This is b

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ecause the hair follicles need to be in a state of growth before the laser treatment can deaden them. Not all hair follicles are a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tivated at the same time. Over a period of about three months all the hair follicles may begin to grow in groups or batches and wh

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

en this happens only then will the treatment be effective.

Why is it still growing?

The reason why hair continu

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s to grow even after a permanent hair removal treatment is because the hair follicles that were not in a state of growth or were i

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nactive during the first session of the permanent hair removal treatment were not affected by the permanent hair removal therapy.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nly the ‘live’ hair follicles were killed by permanent hair removal laser therapy. After the therapy, the inactive follicles start

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ed to grow and this is the hair that grows out, not the treated follicles. This process of inactive follicles growing will continu

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

until all the follicles under the skin have been killed, only then will the hair growth stop.

It does not mean that the treatmen

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

t is ineffective. The treatment needs many sessions until all the follicles are removed. Every time hair grows the treatment must

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

be done to kill the follicles. As time and sessions go by the hair growth will diminish and finally stop. This is achieved within

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

hree to four months and about as many sessions.

Different people react differently to treatment

The effectivene

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ss of the treatment depends on many factors. The candidate must be suited for permanent hair removal treatment. It has been noted

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hat dark people do not react very well to permanent hair removal treatment. This is because the skin absorbs most of the energy fr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

om the laser apparatus and very little energy gets to the hair follicle. This prevents the hair follicle from being deadened by th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

laser energy. Light or red haired people react similarly to permanent hair removal treatment because the hair does not absorb the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

required energy to deaden the follicle.

It is best to take the advice of a specialist before undergoing any permanent hair remov

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

l treatment. Many things must be taken into consideration before undergoing laser hair removal treatment such as having a suntan w

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ill adversely affect the candidate’s over all health. So professional advise before and after the treatment is of prime importance

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Vacations can induce a bout of acid reflux due to irregular meal times, unusual foods, and the basic urge to over indulge in both food and alcohol while at play. For most of us, it really isn't a vacation unless we loosen up a bit, so here are a few tips to help you keep your acid reflux symptoms under control and still enjoy your vacation.

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