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A Sanskrit word meaning ‘yoking’ or ‘union’ , yoga is one of the six orthodox system

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s (darshans) of Indian philosophy, with widespread influence among many other school

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s of Indian thought, one can find its basic text contained in the Yoga-Sutras by Pa

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ta?jali ( c. 2nd B.C.).

Its intellectual content largely based on the philosophy of

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Samkhya, it is the practical aspects of Yoga that play a far more important part in

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

the practice of it. However, it is spiritual release promised by performing yoga th

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

at the yogis or practitioners of it aspire for. Along with Samkhya, Yoga also belie

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ves spiritual liberation is achieved when the self (purusha) frees itself from the b

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ndages of matter (prakriti) that are a direct result of the self’s ignorance and ill

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

usion.

Yoga attempts to reverse this order and helps the self re-enter its original

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

state of purity and consciousness. As soon as the aspirant learns to control the m

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ental activities of the mind, and succeeds in ending all attachment to material obje

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ts, he is able to enter samadhi i.e. a state of deep concentration that results in a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

blissful, ecstatic union with ultimate reality.

This then, is the ultimate goal of

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

every true yogi!

Its intellectual content largely based on the philosophy of Samkh

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ya, it is the practical aspects of Yoga that play a far more important part in the p

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

actice of it. However, it is spiritual release promised by performing yoga that the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

yogis or practitioners of it aspire for. Along with Samkhya, Yoga also believes sp

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

iritual liberation is achieved when the self (purusha) frees itself from the bondage

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s of matter (prakriti) that are a direct result of the self’s ignorance and illusion

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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