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Just what is a silent subliminal message? Surely if you can't hear a silent message it wo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

n't work?

Well yes and no. You see, silent subliminal is really a misnomer. Whilst it's

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

called silent, it isn't really. It's actually either a very high frequency message or a v

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ry low frequency one. Either way, it's inaudible to humans. Which means it really ought t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

o be called an inaudible subliminal. Except that wouldn't sound as catchy.

Silent sublim

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nals have been around for some time. The patent application for them was filed way back i

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

n 1989. You can search it out if you're technically inclined.

Ok, so we've established w

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

at a silent subliminal is.

Now, what do you do with them?

Essentially, they're a hidden

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

communication. Providing that silent subliminals work, they can be added anywhere so lon

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

as the frequency range of the "carrier" medium is wide enough.

Oh, and also if the "car

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

rier" medium doesn't use some kind of lossy compression. So your MP3 collection is almost

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

certainly safe from silent subliminals. MP3's get rid of information that we can't hear

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n order to keep their file size down.

On the other hand, your CD collection could be har

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

boring silent subliminal messages if the artists you listen to are crafty enough to inclu

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e them.

Of course, systems like the Centerpointe Holosync CDs are up front about their u

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

se of silent subliminal messages. In fact, it's part of their selling point.

Rock bands

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ould use silent subliminals. After all, they have been accused of other dodgy practices o

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ver the years, such as including backwards messages in their tracks. Whether or not that

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s true is a matter of conjecture. It could just have been dreamed up by the band's public

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ity department in an effort to encourage rebellious teenagers to buy the music. Who knows

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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