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When we talk about hypnosis or hypnotherapy, we often hear the terms subconscious mind or unconscious mind. It’s become clear to me that there is

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

some degree of confusion over the meaning of the terms, and the difference between the two.

It bears clarifying where the terms came from and how

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and why the terminology has evolved from the Freudian term subconscious mind which society naturally adopted, to the more indicative term unconsci

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

us mind.

In actual fact, in the context of hypnosis, the two terms refer to precisely the same thing, it’s just a matter of which term more appro

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

priately describes the state of being. I am of the opinion that unconscious is the more appropriate choice of word.

Some feel more strongly about

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

it than me. I remember a couple of years ago attending a seminar on hypnosis by my friend who is a very well known hypnotist. Not long after his i

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

troduction speech he told the audience of assembled hypnotherapists “If I hear anyone refer to the unconscious mind as the subconscious mind then

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

I will throw them out of this room”. Of course it was said with a little humour, but his point was clearly made.

I can totally understand the pub

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ic’s use of the word subconscious as the Freudian term was readily adopted by society when the concept of unacknowledged mental activity was disco

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ered. Traditional therapists have historically used the word subconscious, which in my opinion, implies a place that is somehow lessened or belitt

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ed, and undermines the power of the unconscious mind. The prefix ‘sub” suggests something that is somehow beneath par. On the other hand, the term

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

unconscious spells out clearly that it is in fact a part of the mind that is active without our being aware of it.

Outside of the context of hyp

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

osis, people most commonly associate the word unconscious with the state of having completely lost consciousness, or being quite literally knocked

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

out. This is in essence the state of being unaware. By this logic, making reference to the unconscious mind quite appropriately describes the port

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ion of our mind of which we are unaware.

The theory that we only utilize a small part of our brain is misleading in that, we are certainly only c

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nsciously aware of what 10% of our brain is doing at any given moment, but the other 90% is certainly active, we are simply not conscious of it. S

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

when you next hear someone say “we only use 10% of our brains”, challenge them. It’s simply not true!

Anyway, back to the point. To me, the term

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

unconscious is more complimentary, and more effectively defines the power of this part of our mind that we aren’t consciously attentive to. To ca

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

l it subconscious is to suggest that it has less significance or that it doesn’t serve us to an equivalent degree as does our conscious mind. In r

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ality, there is cause to speculate that out unconscious mind may in fact hold greater power than that which we are aware of in our conscious state

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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