Advice Pool - Self Improvement

When you close your eyes and concentrate on what you're experiencing you may find it causes you to ask y

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ourself some pretty weird questions.

"Where am I?"

OK. It may seem obvious on the face of it. You're i

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

your living room, bedroom or wherever. But what evidence of that do you feel? You feel your bum and bac

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

k against the chair, your feet against the floor.

But "where" is the feeling and "where" is the feeler?

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

I used to think that my head is up here and the sensation (of feet on floor) is down there. But, with my

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

eyes closed and concentrating on the present moment, I'm not so sure.

With your eyes closed everything'

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s black. Well, it's not completely black you can see colours but it's nothing to concentrate on, nothing

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

to see. There's no point of reference that says "you are here". No distance. No scale. No comparison.

S

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

metimes when I close my eyes and I'm nicely relaxed I am aware of an incredible sensation of largeness.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Suddenly I am not bounded by four walls or the limit of my eyesight. The result is the universe inside m

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

head.

Try it now! Close your eyes, just briefly, relax and feel the immensity that is larger than anyt

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ing you can imagine.

Now, where are you inside this universe. At what point are you? Are you outside lo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

oking in? Or inside looking out?

If you completely die to the past at every moment there is no "you", n

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

experiencer and experienced, just experience.

In my opinion, this brings us to complete selflessness.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

f there is no you, there is just being. So one is not concerned with one's own welfare!

This may sound

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

like a contradiction, given what I've been saying about selflessness, but when I started self-hypnosis I

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

remember the feeling of complete contentment whilst sitting down and concentrating on my breathing.

And

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

I remember it filtering into the rest of my life. A feeling of happiness coming over me in mundane situa

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tions.

I believe that it is this contentment that can suppress any nicotine, alcohol or drug addiction.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

If I was happy no matter what - I was fed and watered and had no physical pain - why would I need a cig

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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